Home Archive Vol.41, No.3, 2015 Intestinal Microbiome, Small Intestinal Bacterial Overgrowth and Inflammatory Bowel Diseases - What are the Connections?

Intestinal Microbiome, Small Intestinal Bacterial Overgrowth and Inflammatory Bowel Diseases - What are the Connections?

M. Andrei(1), Ș. Gologan(1), Adriana Teiușanu(1), Adriana Stoicescu(1), T. Nicolaie(1), M. DICULESCU(2)

(1)Department of Gastroenterology, Hepatology and Digestive Endoscopy, Elias Emergency Hospital, Bucharest, Romania, (2)Department of Gastroenterology, Hepatology, Digestive Endoscopy, Fundeni Clinical Institute, Bucharest, Romania

    Abstract: IBD (inflammatory bowel diseases) represent chronic idiopathic inflammatory diseases, prone to relapse in the digestive tract; it is estimated that they result from the interaction of the intestinal microbiome with the intestinal immune system. The inflammatory microbiome exerts multiple beneficial roles. Perhaps the central element to developing IBD is dysbiosis; there is still an incompletely established association between intestinal microbiome changes in patients with IBD and SIBO (small intestinal bacterial overgrowth). Influencing the intestinal microbiome may play an adjuvant therapeutic role in the treatment of IBD. We present a synthesis of the connections between the entities mentioned above.
    Keywords: inflammatory bowel disease, small intestinal bacterial overgrowth, intestinal microbiota

DOI 10.12865/CHSJ.41.03.01


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Volume 41 Issue 3 2015