Home Archive Vol.43, No.3, 2017 Correlation between Immunohistochemical Subtype and Clinicopathological Features in Patients with Diffuse Large B-cell Lymphoma

Correlation between Immunohistochemical Subtype and Clinicopathological Features in Patients with Diffuse Large B-cell Lymphoma

ANA-MARIA PATRASCU(1), LILIANA STREBA(2), Ş. PATRASCU(3), JANINA NACEA(1), L. Mogoantă(4), Ionela Rotaru(1)

(1)Department of Hematology, University of Medicine and Pharmacy of Craiova, Romania, (2)Department of Oncology, University of Medicine and Pharmacy of Craiova, Romania, (3)Department of Surgery, University of Medicine and Pharmacy of Craiova, Romania, (4)Department of Histology, University of Medicine and Pharmacy of Craiova, Romania

    Abstract: The aim of this study was to establish correlations between certain clinical, biological, therapeutic factors and diffuse large B-cell lymphoma (DLBCL) subtypes. For this purpose, between January 2007 and December 2016 a total number of 97 patients with de novo diffuse large B-cell lymphoma were analyzed. Patients with a high prognostic index and non-GCB DLBCL positively correlated and exhibited lower survival rates than low IPI, GCB patients. IPI scoring system and cell-of-origin classification should be used together as a single valid prognostic evaluation tool for DLBCL.
    Keywords: diffuse large B-cell lymphoma, international prognostic index, non-Hodgkin lymphoma

DOI 10.12865/CHSJ.43.03.12 


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Volume 43 Issue 3 2017