Home Archive Vol.43, No.3, 2017 Utility of Cerebroplacental Ratio in IUGR Fetuses from Pregnancy with Preeclampsia in Prediction the Risk for Perinatal Complications

Utility of Cerebroplacental Ratio in IUGR Fetuses from Pregnancy with Preeclampsia in Prediction the Risk for Perinatal Complications

MARIA VIOLETA NOVAC(1), AMIRA MOLDOVEANU(1), ŞTEFANIA TUDORACHE(2), NUŢI DANIELA OPRESCU(3), MIHAELA MIESCU(1), MIRELA ANIŞOARA SIMINEL(4), SIDONIA VRABIE(2), M.B. NOVAC(5), D.G. ILIESCU(2)

(1)Ph.D. Student, University of Medicine and Pharmacy of Craiova, Romania, (2)Obstetrics and Gynecology Department, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania, (3)Department of Obstetrics-Gynecology and Neonatology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, (4)Department of Neonatology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania, (5)Anesthesiology and Intensive Care Department, Faculty of Medicine, University of Medicine and Pharmacology of Craiova, Romania

    Abstract: Purpose. The aim of this study was to show that is the incidence of intrauterine growth restriction (IUGR) in women with preeclampsia (PE), assessment of cerebroplacental ratio (CPR) to establish the diagnostic value of CPR in fetuses with preeclampsia with/without IUGR. Material and Methods. We performed an analysis of 49 cases with gestational hypertension and PE and 16 cases with normal pregnancy for control lot, study in Obstetrics and Gynecology Clinic of the Municipal Hospital Filantropia, Craiova, between October 2013 and October 2015. It was performed clinical and laboratory evaluation and management of each case. CPR ratio was measured in the third trimester in all cases, being studied according to the normal and abnormal values obtained, following the evolution of the newborn. Results. Mild PE cases were predominant with 21 cases (19.27%), severe PE accounted for 16 cases (14.68%) and gestational hypertension was found in 16 cases in our study. Distribution of IUGR cases presented interesting and contradictory data, because we met cases of IUGR in pregnancies without PE, at a rate of only 1.54%. The incidence of IUGR was significantly higher in cases with severe early-onset PE (10.20%). Cases of severe PE, but with late-onset, had IUGR in only 2.04% of cases. We found a significant statistical significance (p <0.005) on the incidence of IUGR in cases with severe early-onset PE. CPR identified adverse perinatal outcomes in 18.46% of cases with CPR <1.08. Conclusions. This study shows that early onset severe PE and concomitantly IUGR affects a significant proportion of pregnancies. CPR can be used to identify fetuses with an increased risk of intrauterine compromise.
    Keywords: intrauterine growth restriction, preeclampsia, cerebroplacental ratio

DOI 10.12865/CHSJ.43.03.08 


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Volume 43 Issue 3 2017