Home Archive Vol.43, No.4, 2017 Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment

Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment

CATALINA COTEANU(1), ALICE GUSTI(2), M.F. COTEANU(3), SIMONA GUSTI(4)

(1)Department of Clinical Laboratory, Clinical County Hospital of Craiova, (2)Department of Physiology, Faculty of Physical Education and Sports, University of Craiova, (3)Department of Neurology, County Hospital, Slatina, Romania, (4)Department of Physiology, University of Medicine and Pharmacy of Craiova

    Abstract: In the last 30 years there has been a long way in what concerns the ability to test and diagnose cognitive disorders. On the other hand, it is more and more obvious the necessity to discover new parameters, which can clearly witness the passage from the physiological state of aging to a cognitive impairment in various stages (ranging from mild cognitive impairment to severe dementia). Bringing together all the clinical, paraclinical and neuropsychological data trying to discover the missing link between metabolic disorders, chronic inflammatory changes, progression of atherosclerosis, and the appearance of cognitive disorders, remains an extremely attractive and challenging field of research. By this study, we observed that there is a slight supremacy of the amnestic-MCI in patients with metabolic syndrome, without being able to extract statistically significant data. The interesting data obtained in this study emphasized the connection between the triglycerides/HDL-cholesterol ratio and the presence of the amnestic-MCI subtypes in patients with metabolic syndrome. The data obtained led to the conclusion that an increase in diastolic blood pressure in older people is a prediction factor for cognitive decline.
    Keywords: metabolic syndrome, mild cognitive impairment subtype, triglycerides/HDL-cholesterol ratio

DOI 10.12865/CHSJ.43.04.11 


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Volume 43 Issue 4 2017