Home Archive Vol.43, No.4, 2017 Histopathological Study of Oral Pseudoepitheliomatous Hyperplasia

Histopathological Study of Oral Pseudoepitheliomatous Hyperplasia

Roxana Maria Pascu(1), ŞTEFANIA CRĂIŢOIU(2), ALMA MARIA FLORESCU(1), LUMINIŢA DĂGUCI(1), ILEANA CRISTIANA PETCU(1), EMILIA GEORGIANA PASCU(3), MONICA MIHAELA CRĂIŢOIU(1)

(1)Discipline of Dental Prosthetics, University of Medicine and Pharmacy of Craiova, Romania, (2)Department of Histology, University of Medicine and Pharmacy of Craiova, Romania, (3)Cardiology Clinic of Craiova, Emergency County Clinical Hospital of Craiova, Romania

    Abstract: Pseudoepitheliomatous hyperplasia, also called Heck’s disease, is an epithelial, inconstant and conjunctive proliferation that develops as a response to a great variety of stimuli. It is a lesion associated to different diseases, being found in the following etiopathogenic conditions: infectious pathogenic conditions, tumoral pathogenic conditions, inflammatory pathogenic conditions. We studied oral pseudoepitheliomatous hyperplasia for which we performed a histopathological study, on a group of 47 cases of oral pseudoepitheliomatous hyperplasias, where we investigated the following: oral epithelium changes, changes in the underlying lamina propria and associated etiopathogenic conditions. The main changes of the oral epithelium were: elongation of the epithelial apexes (17.02%), acanthosis (100%), dyskeratosis (14.89%), and in the underlying lamina propria: fibrosis (29.78%), inflammatory infiltrate (70.21%) and vascular proliferation (10.64%). The most frequent associated etiopathogenic conditions were the infectious ones (55.31%), followed by the tumoral ones (29.79%), on the last place being the inflammatory conditions (14.89%).
    Keywords: pseudoepitheliomatous hyperplasia, histopathological study, epithelium, etiopathogenic conditions

DOI 10.12865/CHSJ.43.04.13 


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Volume 43 Issue 4 2017