CHSJ

Curr Health Sci J, vol. 39, no. 2, 2013

Bcl2 gene expression in breast tumors

[Original Paper]

SIMONA DANIELA NEAMTU1, IULIA TUDORASCU1, C. MARGARITESCU1, C.TAISESCU1 , C.TUDORASCU2, MIHAELA NICULESCU1, G. GAMAN1

1 University of Medicine and Pharmacy of Craiova; 2 Hospital of Emergency Medicine Sf.Andrei Galati


Abstract:

Breast cancer is the most common form of woman cancer, it is a major problem for health, being the most common neoplasia with an increased incidence of morbidity and mortality. The overall growth of this form of malignancy of mammary gland disorder requires understanding the various mechanisms involved in tumorgenesis. The appearance of a very rich material and permanent concern of medicine on breast cancer incidence is justified by the occurrence of this type of cancer in young people, both women and men. The diversity of geographical spread of disease requires finding the means of limiting the expansion of therapeutic and aggravation of its evolution. In the aim of increasing life expectancy, genetic studies, the recognition of the intrinsic mechanisms intervening between cells and enter in triggering alteration cell populations involved in healing and therapeutic strategies aimed at discovering, in doing so, they gained a large share.


Keywords: breast cancer, oxidative stress, bcl2, apoptosis



Corresponding: Teaching Assistant Simona Neamtu, M.D., Hematology Department, UMF Craiova, Clinical Laboratory Municipal Hospital Filantropia, st. Constantin Brancusi no.3, Craiova ; e-mail: simona_0712@yahoo.com


DOI 10.12865/CHSJ.39.02.09 - Download PDF
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