CHSJ

Curr Health Sci J, vol. 44, no. 2, 2018

Hepatitis C Infection in Hemodialysis Patients

[Review]

D.C. CARAGEA(1), A.R. MIHAILOVICI(2), C.T. STREBA(3), M. SCHENKER(4), B. UNGUREANU(5), I.N. CARAGEA(1), R. POPA(1), C. OBLEAGA(6), C.C. VERE(5)


(1)Department of Nephrology, University of Medicine and Pharmacy of Craiova, Romania,
(2)Department of Cardiology, University of Medicine and Pharmacy of Craiova, Romania,
(3)Department of Research Methodology, University of Medicine and Pharmacy of Craiova, Romania,
(4)Department of Oncology, University of Medicine and Pharmacy of Craiova, Romania,
(5)Department of Gastroenterology, University of Medicine and Pharmacy of Craiova, Romania,
(6)Department of Surgery, University of Medicine and Pharmacy of Craiova, Romania


Abstract:

Three centuries after the identification of hepatitis C virus (HCV), specialized literature has outlined the epidemiology, viral kinetics and clinical manifestations of this infection. A major cause of morbidity-mortality in patients with renal transplantation and in hemodialysis patients is HCV infection. In high seroprevalence countries, internal accounts are not uniform. The European trend is to decrease the incidence and prevalence of HCV in hemodialysis patients. In Europe, the prevalence of HCV infection among hemodialysis patients tends to be higher than that of the general population, but it is variable by region. Some studies indicate a decrease in incidence in parallel with prevalence in dialysis centers over the last 10 years, while others maintain a high incidence. In some countries, as is the case with Romania, both prevalence and incidence remain high, with the major route of transmission being nosocomial, probably due to limited resources for a rapidly growing dialyzed population. Some authors recommend more isolation measures to be taken in centers with high prevalence of infection.


Keywords: hepatitis C virus, hemodialysis, general data



Corresponding: Alexandru Radu Mihailovici, Department of Cardiology, University of Medicine and Pharmacy of Craiova, 2 Petru Rare Street, 200349 Craiova, Romania, e-mail: drmihailovici@umfcv.ro


DOI 10.12865/CHSJ.44.02.02 - Download PDF
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