CHSJ

Curr Health Sci J, vol. 46, no. 4, 2020

Developmental Abnormalities of the Skull Base in Patients with Turner Syndrome

[Original Paper]

A.I. TECUTA-BUSOI(1), M. MATEI(2), L.M. FLORESCU(3), I.A. GHEONEA(3)


(1)PhD student, Doctoral school, University of Medicine and Pharmacy of Craiova, Romania,
(2)Department of Histology, University of Medicine and Pharmacy of Craiova, Romania,
(3)Department of Radiology and Medical Imaging, University of Medicine and Pharmacy of Craiova, Romania


Abstract:

The skull base is one of the most complex anatomic structures of the skeleton that is responsible for protecting and supporting the brain and is also involved in the development of the facial structures. The main objective of our study was to evaluate skull base abnormalities in a group of patients diagnosed with Turner syndrome by assessing lateral cephalometric radiographs. A total of 7 patients diagnosed with Turner syndrome in the Endocrinology Department of the Emergency Clinical County Hospital of Craiova were included in the study. The following cephalometric variables were measured in our study: total skull base (N-Ba): Nasion (N)-Basion (Ba); anterior skull base (N-S): Nasion (N)-Sella (S); posterior skull base (S-Ba): Sella (S)-Basion (Ba). Regarding the investigated cephalometric variables, the mean±standard deviation (SD) recorded values in our study were 86.34±4.26mm for the total skull base (N-Ba), 63.87±2.54mm for the anterior skull base (N-S) and 38.33±4.87mm for the posterior skull base (S-Ba). The results of our study were compared to the ones provided by one of the most representative studies described in the literature. A reduced size of the posterior base of the skull is considered pathognomonic in subjects diagnosed with Turner syndrome. Also, the posterior base of the skull directly influences the maxillomandibular skeletal relationships and it is therefore necessary to calculate this cephalometric variable, which is easily highlighted on a lateral cephalometric radiograph.


Keywords: Cephalometry, skull base, Turner syndrome.



Corresponding: Lucian Mihai Florescu, M.D., Ph.D, Department of Radiology and Medical Imaging, University of Medicine and Pharmacy of Craiova, Petru Rares 2, 200349, Craiova, Romania, e-mail: lucian.florescu@umfcv.ro


DOI 10.12865/CHSJ.46.04.02 - Download PDF
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