Curr Health Sci J, vol. 49, no. 4, 2023

Update in LV Only Fusion CRT Pacing: Annals and Future Perspectives

[Review]

A. Gurgu(1,3), L. Petrescu(1,3), C.T. Luca(1,2,3), C. Vacarescu(1,2,3), G. Tartea(4,5), E.V. Goana(1,4), L. Cirin(1), D. Cozma(1,2,3)


(1)Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania,
(2)Department of Cardiology, Institute of Cardiovascular Diseases, Timisoara, Romania,
(3)Research Center of Cardiovascular Diseases, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania,
(4)Department of Cardiology, Emergency County Hospital, Craiova, Romania,
(5)Department of Physiology, University of Medicine and Pharmacy Craiova, Romania


Abstract:

Triple-chamber cardiac devices are utilized for cardiac resynchronization therapy (CRT) and is the standard-of-care therapy for heart failure (HF) patients in the current guidelines. In the setting of biventricular (BIV) pacing it involves a mandatory implantation of right ventricular (RV) lead that allows simultaneous BIV pacing with 0 ms VV (ventricular to ventricular) interval. Nevertheless, it seems that response to CRT is not related to RV lead position. RV pacing is known for deleterious effects on RV/Left Ventricle (LV) function and should not be used in persons with normal atrioventricular conduction (AV) and sinus rhythm. As it compensates for the additional asynchrony induced by unnecessary stimulation of RV pacing, only pacing the left ventricle (LV) may result in improved cardiac resynchronization therapy (CRT) outcomes and a decrease in the number of individuals who do not respond to the procedure. Furthermore, leadless LV fusion CRT pacing without RV lead could be a potential CRT therapy alternative to BIV pacing in nonischemic heart failure patients with preserved AV conduction. The aim of our study is to made an update in cardiac resynchronization therapy with LV only fusion pacing.


Keywords:
Heart failure, cardiac resynchronization therapy, LV only pacing, cardiac resynchronization therapy



Corresponding:
Cristina Vacarescu, Department of Cardiology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania, e-mail: cristina.vacarescu@umft.ro


DOI 10.12865/CHSJ.49.04.01 - Download PDF