Curr Health Sci J, vol. 35, no. 1, 2009

Clinical Consequence of the Physicochemical Properties of LDL Particles in Type 2 Diabetes

[Actualities]

Floriana Ionica(1), Florica Popescu(1), Catalina Pisoschi(1), Eliza Gofita(1)


(1)Faculty of Pharmacy, University of Medicine and Farmacy, Craiova


Abstract:

Atherosclerosis is the major cause of death in type 2 diabetes. LDL cholesterol and atherosclerosis are correlated, both in nondiabetes people and those with diabetes, but people with diabetes are more given to atheroma, even though their LDL cholesterol levels are similar. This review analysed the evidence that modification of physicochemical properties of LDL play a role in the accelerated athero-sclerosis associated with type 2 diabetes.


Keywords:
atherosclerosis, diabetes, LDL oxidation, LDL glycation, LDL size



Corresponding:
Assistant. Floriana Ionica MD student, Dept of Toxicology Faculty of Pharmacy, University of Medicine and Pharmacy. Craiova, E-mail: floriana_umf@yahoo.com


DOI 10.12865/CHSJ.35.01.14 - Download PDF