Curr Health Sci J, vol. 36, no. 1, 2010

Cytological And Histopathological Aspects Concerning Preinvasive Squamous Cervical Lesions

[Original paper]

Mihaela Muntean(1), Cristiana Simionescu(2), Rodica Taslica(3) ,Corina Gruia(4), A. Comanescu(5) Nicoleta Patrana(6), Georgiana Fota(4)

(1)Pathological Anatomy Laboratory, Slatina Emergency County Hospital,
(2) Department of Morfopathology, Faculty of Medicine, University of Medicine and Pharmacy, Craiova,
(3)Municipal Hospital Turnu Magurele,
(4)Pathology Laboratory, Emergency County Hospital of Craiova,
(5)Department of Obstetrics-Gynecology, University of Medicine and Pharmacy Craiova,
(6)Pathology Laboratory, County Hospital of RAmnicu-VAlcea


Our study was carried out on a total number of 158 patients, with a mean age of 32, all tested and identified cytologically (Pap-test) as presenting minor cellular abnormalities, respectively ASCUS (10) and LSIL (119), and major cellular abnormalities, respectively SIL-borderline (8) and HSIL (21), and who, either voluntarily or upon cytopathologists’ recommendation, were colposcopically examined. Subsequently, they were subjected to cervical biopsy or excision therapy. In patients with ASCUS cytology, 6 cases were morphologically diagnosed with benign cervical lesions, 3 were diagnosed with LSIL, and one patient was diagnosed as HSIL (CIN 2). Out of 119 LSIL smears 108 were confirmed by histopathology, while 11 were diagnosed as HSIL (CIN 2). In SIL-borderline patients, 5 cases were screened as LSIL and 3 as HSIL. In patients with HSIL cytology, 18 were diagnosed histopathologically as HSIL (CIN 2 and CIN 3/CIS), while 3 were diagnosed as invasive squamous carcinoma.

Pap-test, colposcopic examination, preinvasive cervical lesions.

Muntean Mihaela, MD, Pathological Anatomy Dept., Emergency County Hospital, Slatina;Romania E-mail :

DOI 10.12865/CHSJ.36.01.06 - Download PDF