Curr Health Sci J, vol. 38, no. 4, 2012

Clinical, histological, immunohistochemical and statistical aspects in malignant nasopharyngeal tumors

[Original paper]

I. OSMAN(1), R. MERCUT(2), RAMONA DENISE MALIN(3),GEORGETA OSMAN(1), STEFANIA CRAITOIU(4), VIOLETA COMANESCU(5)


(1) ENT Clinic, County Emergency Hospital, Craiova
(2) Plastic and Reconstructive Surgery Clinic, County Emergency Hospital, Craiova
(3) ENT Clinic, Victor Babes Hospital, Craiova
(4) Histology Department, Medicine and Pharmacy University of Craiova
(5) Pathological Anatomy Department, County Emergency Hospital, Craiova


Abstract:

Various types of cancer can be found at a nasopharyngeal level, and most of them are carcinomas (NPC=nasopharyngeal carcinoma). The most frequent and clinically important carcinoma is the undifferentiated one, known as UCNT. It is localised form, it is a very radiosensitive and radiocurable type of cancer, but strong emphasis has also been placed on its high chemosensitivity. Actually, its connection to the Epstein Barr virus (EBV) drew numerous researchers’ attention. The use of immunohistochemical markers in the study of malignant nasopharyngeal tumours for diagnosis purposes and in order to determine the exact nature of undifferentiated tumours for scientific purposes and for the assessment of the prognosis thus becomes absolutely imperative.


Keywords:
Malignant nasopharyngeal tumors, EBV antibodies, immunohistochemistry, histology, geographical display.



Corresponding:
Ionel Osman MD, ENT Department, County Emergency Hospital Craiova, Tabaci Street, no. 1, Craiova, Romania. Phone number: 0040723571075 E-mail: ionelosm@yahoo.co


DOI 10.12865/CHSJ.38.04.02 - Download PDF