CHSJ

Curr Health Sci J, vol. 39, no. 1, 2013

Study of the risk factors and prevention of venous thromboembolism in surgery

[Original Paper]

M.S. GHELASE(1), A. BORUGA(2), S. RAMBOIU(2), A. ROTARU(2), D. MARGARITESCU(2), D. CARTU(2), F. GHELASE(2)


(1)Department of Public Health and Management, UMF Craiova;
(2)Surgical Specialities I, UMF Craiova


Abstract:

Venous thrombosis is still a major cause for high morbidity and mortality because of its clinical manifestation – deep venous thrombosis (DVT); establishing an early diagnostic is important because thrombosis can rapidly extend to a potentially lethal complication – pulmonary embolism or it can lead to invalidating consequences. Between 2002 and 2006 10653 patients were surgically treated, among them 3875 (45.5%) presented risk factors which could lead to deep venous thrombosis. Patients were grouped according to the involved risk factors in three severity classes: major risk in 1860 cases (47.87%), medium risk in 1300 cases (33.16%) and with low risk 715 (18.56%). Regardless the severity of the risk factors, patients were included in the preventive treatment protocol for deep venous thrombosis, started 1-2 hours before the surgical intervention. Although there are advantages and good results of using low-molecular-weight-heparins (LMWH), we recorded hemorrhagic complications in 79 cases (2.04%), mainly in those with major risk. Surgical reintervention was necessary in 2 cases while treatment reconsideration, conservative measures, reassessment of risk factors and hematological explorations eliminated these adverse effects. Despite the preventive treatment for the venous thrombosis confirmed by Doppler ultrasound scan, we recorded 36 cases of deep venous thrombosis, 12 cases of pulmonary microembolism who received anticoagulation therapy and 3 patients who died from massive pulmonary embolism.


Keywords: venous thrombosis, pulmonary embolism, heparin



Corresponding: M. Ghelase, Department of Public Health and Management, University of Medicine and Pharmacy of Craiova, Str. Petru Rares No 2, 200456, Craiova, Romania


DOI 10.12865/CHSJ.39.01.09 - Download PDF
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