CHSJ

Curr Health Sci J, vol. 40, no. 1, 2014

Pharmacological Mechanisms Underlying the Association of Antipsychotics with Metabolic Disorders

[Review]

ILEANA CRISTINA MIRON(1), VICTORITA CATALINA BAROANA(1), FLORICA POPESCU(2), FLORIANA IONICA(3)


(1)Ph.D. Student in Pharmacology, University of Medicine and Pharmacy of Craiova,
(2)Pharmacology Discipline, Faculty of Medicine, University of Medicine and Pharmacy of Craiova,
(3)Pharmacology Discipline, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova


Abstract:

Obesity and metabolic syndrome in association with an increased risk of cardiovascular disease and type II diabetes are significant problems that contribute to lower life expectancy of patients with schizophrenia. Understanding the pharmacological mechanisms of the current antipsychotic treatment is clearly the key to the improvement of pharmacotherapy, to avoid or to mitigate the metabolic adverse effects.


Keywords: antipsychotic, pharmacological mechanisms, metabolic disorders



Corresponding: Miron Ileana Cristina, Moflesti village, no. 135, Talpas Township, Dolj, e-mail address: mirontia@yahoo.com


DOI 10.12865/CHSJ.40.01.02 - Download PDF
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