CHSJ

Curr Health Sci J, vol. 40, no. 1, 2014

The Assessment of Prognostic Histopatholgical Parameters Depending on Histological Patterns of Papillary Thyroid Carcinoma

[Original Paper]

C. CALANGIU(1), C. SIMIONESCU(1), A. STEPAN(1), M. PARNOV(2), L. CERCELARU(1)


(1)Pathology Department, University of Medicine And Pharmacy of Craiova,
(2)Pathology Department, “Nicolae Testemitanu” State University of Medicine and Pharmacy of Moldavian Republic


Abstract:

Papillary thyroid carcinoma represents common injuries that can have different histological variants that may influence the patient’s prognostic. The study included a total of 44 papillary thyroid carcinomas, for which were followed a series of histological factors of aggressiveness for grading tumors. Most studied papillary carcinomas corresponded to the conventional type, followed by the follicular, micropapillary and tall cell variants. Depending on the presence of nuclear atypia, tumor necrosis, the frequency of mitosis, also the vascular invasion and the extrathyroidian extension there were distributions differences of the cases according to the tumor type, most of the cases belonged to the conventional and tall cell types. The assessment of histopathological parameters of aggressiveness with certain types known to have an unfavorable behavior, justify the use of the histological grading of papillary thyroid carcinomas.


Keywords: papillary thyroid carcinoma, histological grade, tumor type



Corresponding: A. Stepan, Department of Pathology, University of Medicine and Pharmacy of Craiova, 66 1 May Avenue, Craiova 200628, Romania; e-mail: astepan76@yahoo.com


DOI 10.12865/CHSJ.40.01.06 - Download PDF
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