CHSJ

Curr Health Sci J, vol. 41, no. 4, 2015

Molecular Imaging of Cancer Stem Cells for Assessment of Rectal Cancer

[Case reports]

IRINA CHERCIU(1), TATIANA CARTANA(1), IOANA STREATA(2), M. IOANA(2), A. SAFTOIU(3)


(1)Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy of Craiova, Romania,
(2)Human Genomics Laboratory, University of Medicine and Pharmacy of Craiova, Craiova, Dolj, Romania,
(3)Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Romania; Gastro Unit, Division of Endoscopy, Copenhagen University Hospital Herlev, Denmark


Abstract:

Rectal cancer is one of the most common diagnosed malignancies in the world. We present the case of a 54 years old patient, diagnosed with adenocarcinoma of the rectum and unsuccessful treatment. The possible involvement of cancer stem cells in tumor relapse and treatment failure represents the motivation behind an extensive imaging evaluation. The aim of our case report was to assess the outcome of rectal cancer assessment using standard and state-of-the-art techniques, including evaluation of colorectal cancer stem cells. Our results suggest concordant outcomes of modern versus gold standard techniques but further studies are necessary to evaluate the utility during routine clinical work-up.


Keywords: rectal cancer, cancer stem cells, confocal laser endomicroscopy



Corresponding: Adrian Saftoiu, MD, PhD, MSc, FASGE, Visiting Clinical Professor - Gastrointestinal Unit, Copenhagen University Hospital Herlev, Denmark, Professor of Diagnostic and Therapeutic Techniques in Gastroenterology, Research Center of Gastroenterology and Hepatology, Craiova, Romania, University of Medicine and Pharmacy Craiova, Romania, Petru Rares 2, Craiova, Dolj, 200349, Romania. Mobile: + 40 744 823355 , Fax: +40 251 310287, e-mail: adrian.saftoiu@umfcv.ro or adriansaftoiu@aim.com


DOI 10.12865/CHSJ.41.04.16 - Download PDF
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