CHSJ

Curr Health Sci J, vol. 42, no. 1, 2016

Verrucous Carcinoma - Observations on 4 Cases

[Case reports]

V. PATRASCU(1), O. ENACHE(1), R.N. CIUREA(2)


(1)Dermato-venerology Department, University of Medicine and Pharmacy of Craiova;
(2)Pathology Department, University of Medicine And Pharmacy of Craiova


Abstract:

Verrucous carcinoma (VC) is a rare well-differentiated squamous cell carcinoma with the clinical forms: oral florid papillomatosis, epithelioma cuniculatum, papilomatosis cutis and Buschke-Löwenstein tumor. We present four patients and the four clinical forms of CV. The diagnosis we held after clinical examination and histopathological examination of the balance sheet expansion. First described by Ackermanin the oral mucosal, today it has a reported incidence of 1-3 cases per million inhabitants. CV can involve both skin and mucous membranes. Etiopathogenesis is uncertain, but participation HPV is widely accepted. WHO recognizes the CV as a rare form of well-differentiated squamous cell carcinoma with slow and continues evolution, with the invasion of underlying tissues, frequent relapses and very low risk of metastasis. The elective therapy is surgical excision with safety oncological margins. Diagnosis involves corroboration of clinical data with histopathological appearance and evolutive behavior of the tumor. Given the increased risk for recurrence, the patient should be reviewed quarterly to finding healing.


Keywords: Verrucous carcinoma, oral florid papillomatosis., epithelioma cuniculatum, papilomatosis cutis carcinoides, Buschke-Löwenstein tumor



Corresponding: Virgil Patrascu, Universitary Professor, MD, PhD, Department of Dermatology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rares Street, 200349 Craiova, Romania; Tel: +40724-273 676; e-mail: vm.patrascu@gmail.com


DOI 10.12865/CHSJ.42.01.15 - Download PDF
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