CHSJ

Curr Health Sci J, vol. 42, no. 3, 2016

Plant Growth Regulating Activity of Some N-Substituted Chloroacetylanilines

[Original Paper]

GABRIELA RAU(1), CATALINA PISOSCHI(2), O. CROITORU(3), DENISA CONSTANTINA AMZOIU(3), G.D. MOGOSANU(4), ELENA CAMELIA STANCIULESCU(2)


(1)University of Medicine and Pharmacy of Craiova, Faculty of Pharmacy, Department of Organic Chemistry,
(2)University of Medicine and Pharmacy of Craiova, Faculty of Pharmacy, Department of Biochemistry,
(3)University of Medicine and Pharmacy of Craiova, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
(4)University of Medicine and Pharmacy of Craiova, Faculty of Pharmacy, Department of Pharmacognosy and Phytotherapy


Abstract:

Purpose. The synthesis and physico-chemical characterization of six N-substituted chloroacetylanilines and testing their plant growth regulating activity. Material/Methods. The synthesis of the six N-substituted chloroacetylanilines was accomplished by condensation of N-substituted anilines, in an acidic medium, with chloroacetylchloride. Purified compounds obtained were physico-chemical characterized by elemental analysis and spectral analysis. Five different concentrations (0.1%, 0.5%, 0.75%, 1% and 5%) of the compounds solubilized in chloroform were used to analzyed their effects on the germination and mainly on the radicular elongation of wheat caryopses, Triticum aestivum subsp. aestivum (Poaceae), Dropia variety. Results. The N-substituted chloroacetylanilines were solid, differently colored, with high melting temperatures and high yields. Their structure was confirmed both by elemental analysis and by the spectral methods (UV–Vis, FTIR, 1H–NMR, 13C–NMR, GC–MS). Conclusions. For the six analyzed compounds, at five different concentrations (0.1%, 0.5%, 0.75%, 1% and 5%), the experimental data obtained by the method of linear measurement, in the Triticum assay, showed the inhibition of mean radicular elongation compared with the reference


Keywords: N-substituted chloroacetylanilines, melting point, yield, Triticum assay



Corresponding: George Dan Mogosanu, University of Medicine and Pharmacy of Craiova, Faculty of Pharmacy, Department of Organic chemistry. Pharmaceutical chemistry, 2 Petru Rares Street, 200349 Craiova, Romania; e-mail: mogosanu2006@yahoo.com


DOI 10.12865/CHSJ.42.03.05 - Download PDF
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