CHSJ

Curr Health Sci J, vol. 42, no. 3, 2016

Incidence of Pulmonary and/or Systemic Thromboembolism in Pregnancy

[Original Paper]

R.C. PANA(1), LOREDANA MARIA PANA(2), O. ISTRATOAIE(3), LUIZA MARIA DUTA(4), LAVINIA MARIA GHEORMAN(5), VERONICA CALBOREAN(6), MIHAELA POPESCU(7), B. VOINEA(8), V.V. GHEORMAN(9)


(1)Department of Obstetrics and Gynecology,University of Medicine and Pharmacy of Craiova,
(2)Department of Anestesiology and Critical Care, University of Medicine and Pharmacy of Craiova,
(3)Department of Cardiology, University of Medicine and Pharmacy of Craiova,
(4)Department of Radiotherapy, University of Medicine and Pharmacy of Craiova,
(5)Department of Diabetology,University of Medicine and Pharmacy of Craiova,
(6)Department of Cardiology, University of Medicine and Pharmacy of Craiova, resident physician,
(7)Department of Endocrinology, University of Medicine and Pharmacy Of Craiova,
(8)Gynecology Departament of Filantropia Hospital of Craiova,
(9)PhD Student, University of Medicine and Pharmacy of Craiova


Abstract:

Pregnancy associate with thromboembolism is one of leading causes of maternal morbidity and mortality. Worldwide the incidence of pregnancy related venous thromboembolism is approximately 1 in 1500 deliveries. The arterial thromboembolism risk is increased from 3 to 4 fold and the risk of venous thromboembolism is five times higher in a pregnant that in a non-pregnant woman. With an appropriate prophylaxis and therapy, prevention of death from systemic thromboembolism in pregnancy necessitates a high index of clinical suspicion succeeded by a timely and accurate diagnostic approach. In pregnancy the clinical diagnosis of systemic thromboembolism is notoriously difficult due to the overlap of signs and symptoms between the pulmonary embolus with or without deep venous thrombosis. We performed a retrospective study of 86 pregnant women with Pulmonary thromboembolism (PTE) and Deep venous thrombosis (DVT) diagnosed between 2009-2015 in Obstetrics-Gynecology Clinic 1 at Emergency County Hospital of Craiova. Our study evaluated these cases considering frequency, maternal and fetus risk associated with thromboembolism. In 6 years we had 35 women diagnosed as PTE, 8 women diagnosed as DVT and PTE, and 43 patients diagnosed as DVT. The underlying disease in our study was hypertension and the most frequent symptoms reported were dyspnea and limb swelling.(100%).During the third trimester of pregnancy the incidence of PTE was 45% and DVT 57%. 12 cases of DVT were related to thrombophilia. Also we found 25 % of PTE that occurred after cesarean and 8 % of PTE after vaginal delivery. We notice that vaginal delivery is safer than cesarean surgery. Also the importance of third trimester of pregnancy and postpartum it is evident.


Keywords: pregnancy, deep vein thrombosis, pulmonary embolism



Corresponding: Calborean Veronica, Resident Physician In Cardiology, Department of Cardiology, University of Medicine and Pharmacy of Craiova, Petru Rares Street, no.2-4, 200349 - Craiova, Romania; e-mail: calborean.veronica@yahoo.com


DOI 10.12865/CHSJ.42.03.08 - Download PDF
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