CHSJ

Curr Health Sci J, vol. 43, no. 2, 2017

Assessing the Degree of Severity of Acute Pancreatitis by Using Multiparameter Scores

[Original Paper]

ELENA IRINA CALUIANU(1), D.O. ALEXANDRU(2), D. MERCUT(3), M. GEORGESCU(4), E.T. TRASCA(3), MARIA IANCAU(1)


(1)Department of Physiology, University of Medicine and Pharmacy of Craiova, Romania,
(2)Department Medical Informatic and Biostatistic, University of Medicine and Pharmacy of Craiova, Romania,
(3)Department of Surgery, Military Emergency Hospital “Dr. ?tefan Odobleja”, Craiova, Romania,
(4)Department III Functional Sciences Physiology, “Victor Babes” University of Medicine and Pharmacy, Timi?oara


Abstract:

Aim: To establish a clinical severity diagnosis and a therapeutical strategy in acute pancreatitis (A.P.) by using multiparameter bioclinical and morphological scores. Material and Method: 71 patients, diagnosed with A.P., between 2012-2016, admitted to the surgical clinics of the Military Emergency Hospital “Dr. Stefan Odobleja” and the Clinical County Emergency Hospital of Craiova, were investigated, following the severity diagnosis, both at admission and in evolution, with the aim of obtaining an optimal therapeutic approach. The Ranson, Imre, Marshall, Balthazar and EPIC scores were used. Results: By analyzing specially the values of the computer tomography severity index of the study group patients, 14.29% of patients were classified as light severity AP with favorable prognosis, 37.14% of patients moderate severity AP, and 48.57% severe AP. The examination of the CT, one of the most important diagnosis tests for AP, established that 34.29% of patients suffered from AP in Balthazar grade B and 22.85% Balthazar grade C, the severity forms we encountered most in our study. The correlation between HCT (hematocrit) value and Ranson score presents a Pearson correlation coefficient r of-0.339, which indicates the existence of a statistically significant inversely proportional relation. Conclusion: Corroboration of the bioclinical and imagistic data, summed as multiparameter scores, allowed us to classify AP into different severity forms: moderate severity AP (14.29%), moderate-severe AP (37.14%) and severe AP (48.57%), which will then facilitate choosing the right therapeutic approach.


Keywords: multiparameter scores, biochemical and imagistic, acute pancreatitis



Corresponding: M. Georgescu, Department III Functional Sciences Physiology, "Victor Babes" University of Medicine and Pharmacy, Timioara, no. 2, Piata Eftimie Murgu street, Timisoara 300041, e-mail: mgeorgiu83@yahoo.com


DOI 10.12865/CHSJ.43.02.04 - Download PDF
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