CHSJ

Curr Health Sci J, vol. 43, no. 3, 2017

Correlation between Immunohistochemical Subtype and Clinicopathological Features in Patients with Diffuse Large B-cell Lymphoma

[Original Paper]

A.M. PATRASCU(1), L. STREBA(2), S. PATRASCU(3), J. NACEA(1), L. MOGOANTA(4), I. ROTARU(1)


(1)Department of Hematology, University of Medicine and Pharmacy of Craiova, Romania;
(2)Department of Oncology, University of Medicine and Pharmacy of Craiova, Romania; 
(3)Department of Surgery, University of Medicine and Pharmacy of Craiova, Romania; 
(4)Department of Histology, University of Medicine and Pharmacy of Craiova, Romania


Abstract:

The aim of this study was to establish correlations between certain clinical, biological, therapeutic factors and diffuse large B-cell lymphoma (DLBCL) subtypes. For this purpose, between January 2007 and December 2016 a total number of 97 patients with de novo diffuse large B-cell lymphoma were analyzed. Patients with a high prognostic index and non-GCB DLBCL positively correlated and exhibited lower survival rates than low IPI, GCB patients. IPI scoring system and cell-of-origin classification should be used together as a single valid prognostic evaluation tool for DLBCL.


Keywords: diffuse large B-cell lymphoma, international prognostic index, non-Hodgkin lymphoma



Corresponding: S. Patrascu, Department of Surgery, University of Medicine and Pharmacy of Craiova, Romania, Petru Rares St. No 2, Craiova, Romania, e-mail: stef.patrascu@gmail.com


DOI 10.12865/CHSJ.43.03.12 - Download PDF
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