CHSJ

Curr Health Sci J, vol. 43, no. 4, 2017

Histopathological Study of Oral Pseudoepitheliomatous Hyperplasia

[Original Paper]

R.M. PASCU(1), S. CRAITOIU(2), A.M. FLORESCU(1), L. DAGUCI(1), I.C. PETCU(1), E.G. PASCU(3), M.M. CRAITOIU(1)


(1)Discipline of Dental Prosthetics, University of Medicine and Pharmacy of Craiova, Romania; 
(2)Department of Histology, University of Medicine and Pharmacy of Craiova, Romania; 
(3)Cardiology Clinic of Craiova, Emergency County Clinical Hospital of Craiova, Romania


Abstract:

Pseudoepitheliomatous hyperplasia, also called Heck’s disease, is an epithelial, inconstant and conjunctive proliferation that develops as a response to a great variety of stimuli. It is a lesion associated to different diseases, being found in the following etiopathogenic conditions: infectious pathogenic conditions, tumoral pathogenic conditions, inflammatory pathogenic conditions. We studied oral pseudoepitheliomatous hyperplasia for which we performed a histopathological study, on a group of 47 cases of oral pseudoepitheliomatous hyperplasias, where we investigated the following: oral epithelium changes, changes in the underlying lamina propria and associated etiopathogenic conditions. The main changes of the oral epithelium were: elongation of the epithelial apexes (17.02%), acanthosis (100%), dyskeratosis (14.89%), and in the underlying lamina propria: fibrosis (29.78%), inflammatory infiltrate (70.21%) and vascular proliferation (10.64%). The most frequent associated etiopathogenic conditions were the infectious ones (55.31%), followed by the tumoral ones (29.79%), on the last place being the inflammatory conditions (14.89%).


Keywords: pseudoepitheliomatous hyperplasia, histopathological study, epithelium, etiopathogenic conditions



Corresponding: Pascu Roxana Maria, Department of Prosthetic Dentistry, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rares Street, 200349 Craiova, Romania, e-mail: pascuroxana81@yahoo.com


DOI 10.12865/CHSJ.43.04.13 - Download PDF
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