CHSJ

Curr Health Sci J, vol. 44, no. 2, 2018

Severe Thrombocytopenia in Patient with Dermatomyositis

[Case report]

A.D. TUDORANCEA(1), P.L. CIUREA(1), F.A. VREJU(1), E.M. VINTILA(2), S-C. DINESCU(1)


(1)Department of Rheumatology, University of Medicine and Pharmacy of Craiova, Romania,
(2)Department of Gastroenterology and Hepatology, Emergency County Hospital Craiova, Romania


Abstract:

Dermatomyositis (DM) is part of a heterogeneous group of systemic diseases called idiopathic inflammatory myopathies. As in other autoimmune connective tissue diseases (CTD), abnormalities of hematopoietic tissue and/or peripheral blood cells may develop and represent an important prognostic factor. Most common CTD associated with thrombocytopenia (TP) are systemic lupus erythematosus and antiphospholipid syndrome. DM-related TP is less frequent and may develop in the context of an underlying malignancy. Severe TP related to myositis is a very rare occurrence. We report a case of a male patient diagnosed with acute DM, debilitating muscle weakness and rapid development of severe TP.


Keywords: dermatomyositis, thrombocytopenia, idiopathic inflammatory myopathies.



Corresponding: Elena Madalina Vintila, 2 Petru Rares Street, Postal code: 200349, Craiova, Romania, e-mail: vintilamadalina@yahoo.com


DOI 10.12865/CHSJ.44.02.17 - Download PDF
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