CHSJ

Curr Health Sci J, vol. 44, no. 3, 2018

Anaplastic Thyroid Carcinoma with Gastric Metastasis

[Case Report]

A.A.L. CHAVEZ(1), P. IYER(2), I. M. CAZACU(1, 3), M.E. CABANILLAS(2), A. RASHID(4), M.S. BHUTANI(1)


(1)Department of Gastroenterology, Hepatology, and Nutrition, University of Texas-MD Anderson Cancer Center, Houston, Texas, USA,
(2)Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas-MD Anderson Cancer Center, Houston, Texas, USA,
(3)Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Romania,
(4)Department of Pathology, Division of Pathology and Laboratory Medicine-MD Anderson Cancer Center, Houston, Texas, USA


Abstract:

Introduction. Carcinomas of the thyroid gland represent 3% of all malignancies, with 1.3 to 9.8% corresponding to anaplastic thyroid carcinomas (ATC). Metastases are present in 50% of patients when ATC is diagnosed. Gastrointestinal metastases are a rare finding in patients with thyroid carcinoma. Case report. A 68-year old gentleman with a history of papillary thyroid carcinoma (PTC) underwent surgery and radiopharmaceutical therapy. Restaging studies nine months later suggested wall thickening localizing to the distal stomach. Endoscopy results showed a large, infiltrative, subepithelial, and ulcerated gastric mass and biopsies revealed anaplastic thyroid carcinoma Conclusion. Incidental thickening or other findings in the stomach in a patient with ATC without gastrointestinal symptoms should be further investigated with endoscopy and biopsies to rule out gastric metastases from anaplastic thyroid carcinoma.


Keywords: Thyroid, anaplastic thyroid carcinoma, gastric metastasis, endoscopy



Corresponding: Manoop S. Bhutani, MD FASGE, FACG, FACP, AGAF, Doctor Honoris Causa, Walter H Wriston Distinguished Professor, Eminent Scientist of the Year 2008, World Scientist Forum, Director of Endoscopic Research Development and Department of Gastroenterology, Hepatology and Nutrition-Unit 1466, UT MD Anderson Cancer Center 1515 Holcombe Blvd., Houston, Texas, USA 77030-4009, e-mail: manoop.bhutani@mdanderson.org


DOI 10.12865/CHSJ.44.03.14 - Download PDF
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