Curr Health Sci J, vol. 44, no. 3, 2018

Noninvasive Fibrosis Assessment in Chronic Viral Hepatitis C associated with End Stage Renal Disease

[Original Paper]

D.C. CARAGEA(1), B.S. UNGUREANU(2), D.N. FLORESCU(2), P. POPA(2), M.V. SACERDOTIANU(2), D.I. GHEONEA(2), C.C. VERE(2)


(1)Department of Nephrology, University of Medicine and Pharmacy of Craiova,
(2)Department of Gastroenterology, University of Medicine and Pharmacy of Craiova


Abstract:

Introduction. HCV is considered the most encountered viral infection that affect patients after hemodialysis sessions. Even though liver biopsy is considered the golden standard for hepatic diagnosis, additional methods have been used for assessing liver fibrosis. Transient elastography (TE) has evolved as a reference method in some European countries and allows the physician to carry out a fibrosis evaluation in a noninvasive, low-cost and rapid method. Our objective was to assess the efficacy of TE in staging patients with HCV liver disease associated with ESRD, thus choosing the correct moment to perform the procedure. Materials and Methods. We included 34 patients known with ESRD within the regional Nephrology Clinic of Olt County Hospital and also having positive hepatitis C viral liver marker. TE was performed before and hemodialysis and data was analyzed. Results. The patients where we have encountered significant changes were especially within the F0 and F1 stage with a decreas


Keywords:
Chronic viral C hepatitis, transient elastography, end stage renal disease



Corresponding:
Bogdan Silviu Ungureanu, Department of Gastroenterology, University of Medicine and Pharmacy of Craiova, Adress: 66 1 Mai Bvd, 200638 Craiova, Romania, e-mail: bogdan.ungureanu@umfcv.ro


DOI 10.12865/CHSJ.44.03.02 - Download PDF