Curr Health Sci J, vol. 44, no. 3, 2018

Study of Histopatological Parameters of Gastric Carcinomas with Micropapillary Component

[Original Paper]

M. DOBRITOIU(1), A.E. STEPAN(2), C.C. VERE(3), I. CATARAGA(4), C.E. SIMIONESCU(2)


(1)PhD student, University of Medicine and Pharmacy of Craiova,
(2)Department of Pathology, University of Medicine and Pharmacy of Craiova,
(3)Department of Gastroenterology, University of Medicine and Pharmacy of Craiova,
(4)Medical Medfam, BalÈ™, Romania


Abstract:

Micropapillary carcinoma was recently identified as a carcinoma variant characterized by the presence of small clusters of tumor cells located in optically empty spaces. The study included a number of 14 cases represented by surgical excision specimens diagnosed with gastric carcinoma (tubular, papillary and signet-ring) which associated the micropapillary component in variable proportions. Regarding the low-grade tubular carcinomas, the micropapillary component represented less than 25% of the tumor, while in the high-grade tubular carcinomas and papillary carcinomas it represented 25-50%. Among signet-ring carcinomas, the micropapillary component had a percentage of over 50. The depth of invasion was frequently associated with T3 and T4 categories. Lymph nodes metastasis were found in ten cases and distant metastasis were present in three cases. Recognition of the micropapillary component associated with gastric carcinoma represents an aspect of great importance because it is frequen


Keywords:
Gastric carcinoma, micropapillary component, histopathological parameters.



Corresponding:
Alex Emilian Stepan, Department of Pathology, University of Medicine and Pharmacy of Craiova, 66 1 May Avenue, 200628 Craiova, Romania, e-mail: astepan76@yahoo.com


DOI 10.12865/CHSJ.44.03.04 - Download PDF