Curr Health Sci J, vol. 45, no. 3, 2019

Preoperative Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio and Lymphocyte-Monocyte Ratio in Peripheral Blood of Patients with Gastrointestinal Malignant Lesions

[Original Paper]

M.O. PETRESCU (1),D. RADULESCU (1), D. MARINESCU (2),V. SURLIN (2),S. BORDU (2), G.S. PETRESCU (1)

1) PhDstudent,UniversityofMedicineandPharmacyofCraiova,Romania 2) DepartmentIofSurgery,UniversityofMedicineandPharmacyofCraiova,Romania


Abstract:

Localinflammationplaysaveryimportantroleintheapparitionanddevelopmentoftumorsandmetastasis.Theobjectiveofthisstudywastoinvestigatethesignificanceofneutrophiltolymphocyteratio(NLR),lymphocytetomonocyteratio(LMR)andplatelettolymphocyteratio(PLR)inperipheralbloodofpatientswithgastrointestinalmalignanttumors.Methods:Medicalrecordsof145patientsdiagnosedwithgastrointestinalmalignanttumorbetweenJanuary2017andDecember2017wereanalyzedretrospectively.Pretreatmentneutrophil,lymphocyte,plateletandmonocytecountsandNLR,LMRandPLRwereinvestigated.Results:ThemeanforNLR,PLRandLMRinpatientswithgastrointestinalcancerweredetermined.Conclusions:DeterminationofNLR,PLRandLMRcanbeeasilydonewithasimplebloodtestandmaybeusefulinflammatorymarkersasinourstudywehaveobservedthepresenceofincreasedinflammatoryresponseinpatientswithgastrointestinalcancer.


Keywords:
Lymphocytetomonocyteratio(LMR),neutrophiltolymphocyteratio(NLR),andplatelettolymphocyteratio(PLR),cancer,malignlesions,gastrointestinal



Corresponding:
Gabriel-SebastianPetrescu,PhD student, UniversityofMedicineandPharmacyofCraiova,Romania,Str.PetruRaresno.2-4,Craiova200349,Romania,e-mail:sebigabriel_petrescu@yahoo.com


DOI 10.12865/CHSJ.45.03.06 - Download PDF