Curr Health Sci J, vol. 45, no. 4, 2019

Correlations Between Clinicopathological Features and the Vegetative Nervous System in Gastric Cancer

[Original Paper]

A.M. BALEA (1,2), R. CRUCE (3), R.A. SCHENKER (1,2), A.G. IONESCU (4), L. STREBA (5), A.M. CIUREA (1,2), M.C. GHILUSI (6), D. PIRICI (3), C.C. VERE (7)

1) PhD student, University of Medicine and Pharmacy of Craiova, Romania 2) Sf. Nectarie Oncology Center, Craiova, Romania 3) Department of Research Methodology, University of Medicine and Pharmacy of Craiova, Romania 4) Department of Medical History, University of Medicine and Pharmacy of Craiova, Romania 5) Department of Oncology, University of Medicine and Pharmacy of Craiova, Romania 6) Department of Pathology, County Emergency Hospital of Craiova, Romania 7) Department of Gastroenterology, University of Medicine and Pharmacy of Craiova, Romania


Abstract:

Gastric cancer currently represents one of the most important public health problems. Recent studies have demonstrated the existence of strong correlations between the vegetative nervous system and the role it plays in the initiation of the oncogenetic process and the progression of cancer. The purpose of this paper is to demonstrate the involvement of the sympathetic and parasympathetic vegetative nervous system in the evolution of gastric cancer, according to the stage of tumor differentiation. In this current paper we have included a number of four patients diagnosed with gastric cancer post UGI (Upper Gastrointestinal Endoscopy) and have analyzed relations that exist between the tumor differentiation degree and the metanephrine and normetanephrine serum level in the blood of the patients. Following the research, we have observed an increased value of the metanephrine and normetanephrine serum level in the patient which displayed the lowest degree of differentiation.


Keywords:
Gastric cancer, metanephrine, normetanephrine, differentiation degree



Corresponding:
Ramona Adriana Schenker, Clinical Psychologist, PhD student, University of Medicine and Pharmacy of Craiova, 2-4 Petru Rares St., Craiova, Romania, e-mail: ramona_schenker@yahoo.com


DOI 10.12865/CHSJ.45.04.02 - Download PDF