Curr Health Sci J, vol. 46, no. 3, 2020

The Impact of the Associated Pathology in Acute Coronary Events

[Original Paper]

S.N. DINESCU(1), R.C. VASILE(1), M.M. FRUNZULICA(2), V.C. DINESCU(3), E. BURADA(4), A. TANASIE(4), C.E. BICA(5), V. GHEORMAN(6), O.S. GEORGESCU(2), F.M. ROMANESCU(4)


(1)Epidemiology Department, University of Medicine and Pharmacy of Craiova, Romania,
(2) 2PhD, University of Medicine and Pharmacy of Craiova, Romania,
(3)Health Promotion Department, University of Medicine and Pharmacy of Craiova, Romania,
(4)Physiology Department, University of Medicine and Pharmacy of Craiova, Romania,
(5)Paediatrics Department, University of Medicine and Pharmacy of Craiova, Romania,
(6)Psychiatry Department, University of Medicine and Pharmacy of Craiova, Romania


Abstract:

Acute coronary events (ACE) are one of the main concerns for both clinical medicine and prophylaxis. The study aims to follow the frequency of the pathology associated with ACE and to establish its association with the occurrence of ACE. The study included 865 adult participants between the ages of 19-86. Subjects completed a complex questionnaire that included questions about health status. The study was conducted by applying the subjects to an anonymous questionnaire, in three family medicine practices between November 2018 to May 2019 and targeted healthy people. The frequencies of the following types of associated pathologies were evaluated: high blood pressure (HBP), hypercholesterolemia, stroke, diabetes, depression, stress. In hypertensive patients the prevalence of ACE was 6,99% (N=11) and in those not diagnosed with HBP of only 0,29% (N=2). The risk of ACE was 20 times higher than in those without HBP (RR=20,93; p<0.001). The prevalence of ACE was high among subjects with high cholesterol levels (21,43%) compared with those with normal values (3,03%; N=22), the risk of ACE being 7 times higher (RR=7,06; p<0.001). The prevalence of diabetes was more than four times higher in subjects with ACE (17,3%; N=9) compared with those without ACE (3,9%; N=32). Among those affected by diabetes, the prevalence of ACE was 21,95% (9/41), and risk of ACE in people with diabetes was four times higher (RR=4,21; p<0.001). Although cardiovascular disease is the most common pathology in the contemporary world, a number of comorbidities arise as ACE generators (hypertension, hypercholesterolemia, diabetes), along with psycho-emotional disorders such as depression, anxiety or stress, which outline, ensures, contributes or accelerates the progression to ACE.


Keywords:
Acute coronary event, high blood pressure, cholesterol level, stroke, diabetes, depression.



Corresponding:
Ovidiu Stefan Georgescu, PhD, University of Medicine and Pharmacy of Craiova, 2 Petru Rare Str., 200349, Craiova, e-mail: georgescuovi@yahoo.com


DOI 10.12865/CHSJ.46.03.10 - Download PDF