Curr Health Sci J, vol. 47, no. 1, 2021

Basal Cell Carcinoma and its Impact on Different Anatomical Regions

[Original Paper]

A. Cojocaru(1), E.A. Marinescu(2), O. Nica(2), E. Ilinoiu(2), A. Negrila(2), M.E. Ciurea(2)

(1)Department of Dermatology, University of Medicine and Pharmacy of Craiova, Romania,
(2)Department of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania


Basal cell carcinoma (BCC) is the most common skin cancer. We conducted a retrospective study over a period of two years (2018-2019), on 214 patients from the Plastic Surgery clinic in order to identify the clinical and histopathological aspects of the disease: the case distribution according to sex, living environment, age, histopathological subtype, location. Results. The F/M ratio was of 1.03 in favour of women. The incidence was higher for patients from rural areas (55.14%). The most affected group age was between 70-80 years old, with 76 patients (35.51%). The most frequent histological type was nodular basal cell carcinoma (65.42%), followed by micronodular subtype (17.29%). We observed the association of basal cell carcinoma with a number of other conditions such as: high blood pressure (92 cases), diabetes (19 cases), chronic kidney disease (2 cases), liver disease (5 cases), epilepsy (2 cases). Correlating the histopathological subtype and the invasion of the edges of the surgical excision specimen, we noticed that edge invasion was present: in the case of nodular basal cell carcinoma (15.71%), micronodular subtype (43.24%), superficial subtype (50%), morpheaform subtype (40%). Dividing the cases by location, we highlighted the risk areas: nasal region (29.44%), cheek (10.75%), orbital region (13.55%), scalp (10.75%), auricular region (7.48%), forehead (8.41%), etc. Thus, 89.72% of cases were located on photo-exposed areas (head and neck). Patients from rural areas registered a higher number of cases both in photo-exposed and non-exposed areas.

Basal cell carcinoma, histopathological subtype, location, risk areas

Elena-Alexandra Marinescu, PhD Student, Department of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania, 2 Petru Rare St., e-mail:

DOI 10.12865/CHSJ.47.01.12 - Download PDF