Curr Health Sci J, vol. 47, no. 2, 2021

Maternal Lipid Profile as a Risk Factor for Gestational Diabetes Mellitus in Obese Women

[Original Paper]

Carmen Tabacu(1), Maria-Magdalena Manolea(1), Liliana Novac(1), Anda Lorena Dijmarescu(1), Mihail Virgil Boldeanu(2)


(1)Obstetrics and Gynecology Department, University of Medicine and Pharmacology of Craiova, Romania,
(2)Immunology Department, University of Medicine and Pharmacy of Craiova, Romania


Abstract:

As dyslipidemia is frequently associated with gestational diabetes mellitus, the aim of this study was to establish a correlation between the evolution of the maternal lipid profile evaluated in the first and third pregnancy trimester for a series of parameters: triglycerides, cholesterol, high-density lipoprotein cholesterol (HDL-C), blood sugar fasting (BSF), triglyceride-glucose index (TyG index), TG/HDL-C ratio, leptin and the risk of gestational diabetes mellitus occurrence. The results were statistically interpreted, establishing the mean value of the obtained results and the standard deviation. From the studied parameters, only HDL-C and Tyg were statistically significant different in the first trimester for the two study groups, while in the third trimester statistically significant differences were observed also for triglycerides, blood sugar fasting and the TG/HDL-C ratio.


Keywords:
Gestational diabetes mellitus, lipid profile, obesity



Corresponding:
Maria-Magdalena Manolea, Obstetrics and Gynecology Department, University of Medicine and Pharmacology of Craiova, Romania, e-mail: magdalena.manolea@umfcv.ro


DOI 10.12865/CHSJ.47.02.10 - Download PDF