Curr Health Sci J, vol. 47, no. 3, 2021

The Unusual Presentation of a Single Case of Synchronous Metastatic Clear Cell Renal Cell Carcinoma to the Gallbladder: A Case Report and Literature Review

[Case Report]

G.T. Patterson(1), A. Ullah(2), I. Elhelf(3), R. Madi(4), S.K. Kavuri(2), N.A. Karim(5)

(1)Medical College of Georgia, Augusta University, Augusta, GA, USA,
(2)Department of Pathology, Augusta University, Augusta, GA, USA,
(3) Department of Radiology and Imaging: diagnostic, Augusta University, Augusta, GA, USA,
(4)Department of Surgery: Urology, Augusta University, Augusta, GA, USA,
(5)Department of Medicine: Hematology and Oncology, Augusta University, Augusta, GA, USA


Clear cell renal cell carcinoma, accounts for approximately 70% of all adult renal tumors. This disease is well known for its high metastatic potential, with estimates of 25-50% of patients reporting metastasis to distant structures. However, there have only been several reported cases in medical literature describing hematogenous spread to the gallbladder, with the majority occurring metachronously, in males, and with multiple metastases. This case report follows an extremely unique presentation in a 60-year-old female. Although the patient did not exhibit the usual signs and symptoms or meet the typical demographics seen with metastatic renal cell carcinoma, it should find a place on the differential diagnosis list when a gallbladder lesion is detected on imaging during the initial staging and/or restaging in patients with renal-cell carcinoma.

Clear cell, renal, carcinoma, metastatic, synchronous, gallbladder.

Gregory Taylor Patterson, Medical College of Georgia, Augusta University, Augusta, GA, e-mail:

DOI 10.12865/CHSJ.47.03.19 - Download PDF