CHSJ

Curr Health Sci J, vol. 47, no. 4, 2021

The Importance of Magnetic Resonance in Detection of Cortical Dysplasia

[Case Report]

F. Hyseni (1), I. Ahmetgjekaj (2), V. Vokshi (3), K. Mamillo (4), V. Biba (5), B. Shaipi (6), M. Brati (7), K. Dedushi(2), J. Shatri (2), E. Aliu (8), A. Guy (9), K. Salihaj (5), R. Berisha (10), J. Musa (11)


(1)Medical Researcher, NYU Langone Health, New York, USA,
(2)Clinic of Radiology, University Clinical Center of Kosovo, Albania,
(3)Department of Anesthesiology and Reanimation, University Clinical Center of Kosovo, Albania,
(4)Department of Anesthesiology and Critical Care, Mother Teresa Hospital, Tirana, Albania,
(5)Mother Teresa Hospital Center, Tirana, Albania,
(6)University of Medicine, Tirana, Albania,
(7)Albert Einstein College of Medicine, Department of Psychiatry and Behavioral Sciences, New York, USA,
(8)Department of Radiology, General Hospital, Gjilan, Kosovo,
(9)Department of Rehabilitation Medicine, NYU Grossman School of Medicine, New York, USA,
(10)Department of Radiology, Hospital of Pneumo-Phthisiology, Leamna, Romania,
(11)Department of General Surgery, Mayo Clinic, Rochester, MN, USA


Abstract:

Focal cortical dysplasia is a malformation of cortical development in which there are abnormalities with cortical lamination, neuronal maturation, and neuronal differentiation. It is the most common cause of medically refractory epilepsy in the pediatric population and the second/third most common etiology of medically intractable seizures in adults. Herein, we present the case of 23-years-old female patient, presenting with loss of consciousness, and convulsions. A MRI revealed a 5mm cortical thickening on either side of the posterior aspect of the right superior temporal gyrus without transmantle extension towards ventricle. This abnormal area is measured about 24x16mm and there was no evidence for mesial temporal sclerosis. Both hippocampi are normal is size, morphology and signal. These features are consistent with cortical dysplasia type 1. This case report emphasizes the importance of MRI in the detection of FCD. MRI can show no abnormalities in type 1 FCD, but when the changes are apparent, they are on the temporal lobe, and seizures presents most commonly in adults.


Keywords: Focal cortical dysplasia, cortical development, neuronal maturation, hippocampus.



Corresponding: lir Ahmetgjekaj, Clinic of Radiology, University Clinical Center of Kosovo, Albania, e-mail: drilir@hotmail.com


DOI 10.12865/CHSJ.47.04.16 - Download PDF
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