Curr Health Sci J, vol. 48, no. 3, 2022

A Rare Case of Neglected Giant Basal Cell Carcinoma in a Nurse-Case Report and Literature Review

[Case Report]

A. Cojocaru(1,2), O.A. Orzan(2,3), C. Birjovanu(1,4), N.C. Andreea(5), D. Petrache(6), E.M. Marinescu(7), M.E. Ciurea(7)


(1)PhD Student, Doctoral School, University of Medicine and Pharmacy of Craiova, Romania,
(2)Department of Dermatology, Elias Emergency University Hospital, Bucharest, Romania,
(3)Department of Dermatology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,
(4)Department of Ophthalmology, “Dr. Carol Davila”, Central Military Emergency University Hospital, Bucharest, Romania,
(5)Department of Histology, Emergency University Hospital, Bucharest, Romania,
(6)Private consultant-Savigneux, France,
(7)Department of Plastic Surgery, University of Medicine and Pharmacy of Craiova, Romania


Abstract:

Basal cell carcinoma (BCC) is the most common skin cancer in the fair-skinned adult population over 50 years of age and the incidence is rising. Generally, BCC has an indolent course, low mortality and a good prognosis due to low rates of metastasis. Giant basal cell carcinoma is a rare reported oncological entity which accounts for 0.5% to 1% of all cases of BCC and has a diameter larger than 5cm. Basosquamous carcinoma is a rare high-risk type of BCC with clinical and histopathological features of both BCC and squamous cell carcinoma. A 61-year-old female presented to our clinic for a giant bleeding tumor located under her left breast. She initially noted the tumor almost 15 years ago. Although the patient was a nurse, she was afraid to seek medical advice until an episode of significant bleeding. At presentation the tumor was a 15/7cm in size, was invading the underlying structures and had a central ulceration. The margins of the tumoral plaque had several nodules and pearly structures suggesting the possible clinical diagnosis of BCC.


Keywords:
Basal cell carcinoma, giant basal cell carcinoma, basosquamous carcinoma.



Corresponding:
Olgua-Anca Orzan, "Carol Davila" University of Medicine and Pharmacy, Bucharest 050474, Romania, e-mail: olguta@gmail.comAlexandra Roman, Department of Periodontology, Iuliu Haieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania, e-mail: veve_alexandra@yahoo.com


DOI 10.12865/CHSJ.48.03.13 - Download PDF