CHSJ

Curr Health Sci J, vol. 49, no. 2, 2023

The Role of Uterine Artery Doppler in the Second and Third Trimesters for Prediction of Preeclampsia and Fetal Growth Restriction Developed as a Consequence of Placental-Mediated Diseases

[Original Paper]

A Tudor(1), L Novac(2), IV Camen(1,6), MM Manolea(2,6), MS Sandulescu(2,6), SC Vrabie(2,6), MS Serbanescu(3), MV Boldeanu(4), AM Istrate-Ofiteru(5), AL Dijmarescu(2,6)


(1)Doctoral School, University of Medicine and Pharmacology of Craiova, Romania,
(2)Obstetrics and Gynecology Department, University of Medicine and Pharmacology of Craiova, Romania,
(3)Medical Informatics Department, University of Medicine and Pharmacology of Craiova, Romania,
(4)Immunology Department, University of Medicine and Pharmacy of Craiova, Romania,
(5)Department of Histology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania,
(6)Obstetrics and Gynecology Department, “Filantropia” Hospital, Craiova, Romania


Abstract:

Placenta-mediated pregnancy disorders represent a disease that includes preeclampsia (PE) and the birth of small for gestational age (SGA) children, these conditions increase the risk of mortality and morbidity both maternal and fetal/neonatal, in the short and long-term. Methods: The prospective study included 106 patients in whom ultrasound Doppler scans of uterine artery (UtA) were performed in the 2nd trimester between 20.0-23.6 weeks of gestation and the 3rd trimester between 28.0-32.6 weeks of gestation. Results: In the second trimester, the average of the UtA-PI percentiles was statistically significant (p<0.05) in correlation with PE and SGA, as in the third trimester. Statistically significant (p<0.05) was also the correlation of UtA-PI >95 percentile with the development of PE and SGA. On the other hand, the present notch, in the two trimesters studied, analyzed as a single index, did not present a statistically significant association (p>0.05). Conclusions: The results of our study showed that UtA-PI Doppler is the best predictor of preeclampsia considering the association of intrauterine growth restriction, as most studies have found.


Keywords: Doppler ultrasonography, UtA, PE, SGA



Corresponding: Maria Magdalena Manolea, Obstetrics and Gynecology Department, University of Medicine and Pharmacology of Craiova, e-mail: manoleamaria@gmail.com


DOI 10.12865/CHSJ.49.02.15 - Download PDF
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