Curr Health Sci J, vol. 49, no. 3, 2023

Probe - Based Confocal Endomicroscopy and Endoscopy in NBI Module - The Role in Clinical Decision - Case Reports

[Case Report]

P. POPA(1), M. MATEI(2), L. STREBA(3), M.M. FLORESCU(4), C.T. STREBA(1)


(1)Department of Gastroenterology, Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy of Craiova, Craiova, Romania;
(2)Department of Histology, University of Medicine and Pharmacy of Craiova, Craiova, Romania;
(3) Department of Oncology, University of Medicine and Pharmacy of Craiova, Craiova, Romania;
(4)Department of Pathology, University of Medicine and Pharmacy of Craiova, Craiova, Romania


Abstract:

Cancer remains a significant global cause of mortality, irrespective of a country's level of development. Among all cancer types, gastrointestinal cancers claim the highest number of lives annually. This disease predominantly affects individuals in their 6th to 8th decades of life. Unfortunately, diagnoses often occur during advanced stages of the illness, rendering chemotherapy less effective and offering a reserved prognosis. Conventional endoscopy, however, struggles to differentiate lesions based on their histological composition. Consequently, the management of patients largely depends on histopathological examinations, which can be time-consuming. Biopsy results are sometimes delayed, with precious weeks passing, particularly critical for patients with malignant lesions. Moreover, biopsies may yield inconclusive results if not precisely targeted, leading to potential mismanagement, unnecessary resections and burdensome pathology services. This series of cases underscores, as previous studies have, the value of modern endoscopic techniques in determining the appropriate therapeutic approach for each patient, an approach that ensures the highest quality of life.


Keywords:
Colonoscopy, NBI, pCLE, polips



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DOI 10.12865/CHSJ.49.03.16 - Download PDF