Curr Health Sci J, vol. 49, no. 4, 2023

When a Chorangioma Becomes a Burden in Fetal Survival: A Reported Case with an Updated Literature Review

[Case Report]

D. BURLACU(1,2), A. BURLACU(1), R. BELENYESSY(3), B.SZABO(1,4), T. MEZEI(1,2)


(1)George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania;
(2)Targu-Mures Emergency Clinical Hospital, Department of Pathology;
(3)City Hospital of Odorheiu Secuiesc, Romania;
(4)Targu-Mures Emergency Clinical Hospital, Obstetrics and Gynecology Clinic


Abstract:

Chorangioma is a rare non-trophoblastic benign vascular neoplasm originating from the primitive chorionic mesenchyme. Usually asymptomatic, it affects approximately 1% of female fetuses. We present the case of a giant placental chorangioma (GPC) in a preterm male pregnancy coexisting with a maternal neuroendocrine carcinoma. A 30-week primigravida was admitted to the Obstetrics and Gynecology Clinic of the Targu-Mures Emergency Clinical Hospital, with abdominal discomfort, and an emergency C-section was performed for fetal congestive heart failure. Medical history revealed an advanced-stage rectal neuroendocrine carcinoma. At 20th gestational week, a well-vascularized placental mass was diagnosed. A 1500g premature male fetus was delivered. Histopathologically, the placental mass revealed an unencapsulated but well-circumscribed tumor with lobular architecture composed of congested vascular capillaries and thin-walled vessels. Diagnosis of giant placental chorangioma (GPC) was rendered. GPC is a challenging condition typically occurring in hypertensive or diabetic primigravidas with female fetuses. Antenatal management is suggested at an early stage for a desirable perinatal outcome.


Keywords:
Chorangioma, placenta, benign, vascular, prematurity.



Corresponding:
Diana Burlacu, PhD student, 3rd year resident in Pathology Department of Targu-Mures Emergency Clinical Hospital, e-mail address: dianaburlacu@yahoo.com


DOI 10.12865/CHSJ.49.04.18 - Download PDF